Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542843 | 0.90 | MAOA (0.41) | KMT2AMEN1USP2CYP2C9ABCB1 | |
| SCHEMBL9348186 | 0.84 | CYP2C9 (0.39) | KMT2AMEN1USP2CYP2C9ABCB1 | |
| SCHEMBL9345601 | 0.79 | CYP2C9 (0.38) | KMT2AMEN1USP2CYP2C9ABCB1 | |
| SCHEMBL8787996 | 0.78 | KMT2A (0.39) | KMT2AMEN1USP2ABCB1TSHR | |
| SCHEMBL7422948 | 0.78 | KMT2A (0.41) | KMT2AMEN1USP2ABCB1TSHR | |
| SCHEMBL8427998 | 0.78 | KMT2A (0.41) | KMT2AMEN1USP2ABCB1TSHR | |
| SCHEMBL5542835 | 0.73 | ABCB1 (0.41) | KMT2AMEN1USP2ABCB1TSHR | |
| SCHEMBL13062858 | 0.71 | ABCB1 (0.57) | KMT2AMEN1USP2ABCB1TSHR | |
| SCHEMBL12236947 | 0.71 | ABCB1 (0.41) | KMT2AMEN1USP2ABCB1TSHR | |
| SCHEMBL22519097 | 0.70 | ABCB1 (0.36) | CYP2C9ABCB1LTB4RLTB4R2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112261-B1 | 2-ETHYL-2,3-DIHYDROBENZOFURAN-CARBOXYLIC ACID ESTER DERIVATIVE, PREPARATION METHOD AND USE FOR PREPARING EFAROXAN DERIVATIVES | PIERRE FABRE SANTE S A (FR) | 2002-04-10 | — | — | EP | disclosed |
| EP-1112261-A1 | 2-ETHYL-2,3-DIHYDROBENZOFURAN-CARBOXYLIC ACID ESTER DERIVATIVE, PREPARATION METHOD AND USE FOR PREPARING EFAROXAN DERIVATIVES | PIERRE FABRE SANTE S.A. (FR) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015624-A1 | 2-ETHYL-2,3-DIHYDROBENZOFURAN-CARBOXYLIC ACID ESTER DERIVATIVE, PREPARATION METHOD AND USE FOR PREPARING EFAROXAN DERIVATIVES | PIERRE FABRE SANTE, SOCIETE ANONYME (FR) | 2000-03-23 | — | — | WO | disclosed |