SCHEMBL5543153

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10053486	0.82	ALDH1A1 (0.70)	NOTUMPOLBALDH1A1LMNAHTT
	SCHEMBL29715598	0.79	ALDH1A1 (0.50)	NOTUMALDH1A1LMNAHTTL3MBTL1
	SCHEMBL27610352	0.79	POLB (0.52)	NOTUMPOLBALDH1A1LMNAHTT
	SCHEMBL3056133	0.79	ALDH1A1 (0.49)	NOTUMALDH1A1LMNAHTTL3MBTL1
	SCHEMBL18496495	0.79	SMN1; SMN2 (0.65)	NOTUMALDH1A1LMNAHTTL3MBTL1
	SCHEMBL5540345	0.79	LMNA (0.50)	NOTUMPOLBALDH1A1LMNAHTT
	SCHEMBL1353845	0.79	ALDH1A1 (0.50)	NOTUMALDH1A1LMNAHTTL3MBTL1
	SCHEMBL4213757	0.78	ALDH1A1 (0.64)	NOTUMPOLBALDH1A1LMNAHTT
	SCHEMBL20646850	0.78	TP53 (0.50)	NOTUMPOLBALDH1A1LMNAL3MBTL1
	SCHEMBL2736476	0.77	LMNA (0.57)	POLBALDH1A1LMNAHTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.