SCHEMBL5543409

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5544414	0.88	PGR (0.38)	ALDH1A1KMT2AMEN1PGRTP53
	SCHEMBL5542087	0.85	MEN1 (0.45)	ALDH1A1KMT2AMEN1LMNATP53
	SCHEMBL5546476	0.84	SCN9A (0.44)	ALDH1A1KMT2AMEN1
	SCHEMBL5548195	0.83	SCN9A (0.43)	KMT2AMEN1
	SCHEMBL5543415	0.82	CYP2C9 (0.49)	AURKAAURKBALDH1A1KMT2APKM
	SCHEMBL1368159	0.81	ATAD2 (0.48)	AURKAAURKBALDH1A1KMT2APKM
	SCHEMBL5539731	0.78	MEN1 (0.50)	KMT2APKMMEN1TP53
	SCHEMBL5541199	0.77	MEN1 (0.33)	KMT2AMEN1
	SCHEMBL9199579	0.77	ELANE (0.43)	AURKAAURKBALDH1A1KMT2APKM
	SCHEMBL12659677	0.77	AURKA (0.38)	AURKAAURKBALDH1A1KMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.