Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10223234 | 0.86 | CA12 (0.68) | CA12CA1CA2CA9MAPT | |
| SCHEMBL2745785 | 0.84 | CA12 (0.64) | CA12CA1CA2CA9MAPT | |
| SCHEMBL10266158 | 0.82 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2KMT2ALMNAGAA | |
| SCHEMBL1968355 | 0.82 | CA12 (0.66) | CA12CA1CA2CA9MAPT | |
| SCHEMBL22126639 | 0.82 | CA12 (0.53) | CA12CA1CA2CA9MAPT | |
| SCHEMBL903446 | 0.81 | CA12 (0.64) | CA12CA1CA2CA9MAPT | |
| SCHEMBL16115911 | 0.81 | CA12 (0.64) | CA12CA1CA2CA9MAPT | |
| SCHEMBL31432851 | 0.81 | CA12 (0.64) | CA12CA1CA2CA9MAPT | |
| SCHEMBL5540930 | 0.81 | MTNR1A (0.54) | ALDH1A1SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL3345207 | 0.81 | CA12 (0.68) | CA12CA1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |