Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2746596 | 0.86 | MTNR1A (0.56) | MTNR1AMTNR1BSLC2A1ALDH1A1MEN1 | |
| SCHEMBL25300742 | 0.84 | MTNR1A (0.56) | MTNR1AMTNR1BSLC2A1ALDH1A1MEN1 | |
| SCHEMBL30517507 | 0.84 | MTNR1A (0.56) | MTNR1AMTNR1BSLC2A1ALDH1A1MEN1 | |
| SCHEMBL7281747 | 0.83 | MTNR1A (0.55) | MTNR1AMTNR1BSLC2A1ALDH1A1MEN1 | |
| SCHEMBL13774782 | 0.81 | OPRK1 (0.68) | ALDH1A1MEN1KMT2AOPRK1SMN1; SMN2 | |
| SCHEMBL5543465 | 0.81 | CA12 (0.61) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL10163435 | 0.80 | MTNR1A (0.62) | MTNR1AMTNR1BSLC2A1ALDH1A1MEN1 | |
| SCHEMBL12707505 | 0.80 | SLC2A1 (0.58) | MTNR1AMTNR1BSLC2A1ALDH1A1MEN1 | |
| SCHEMBL441815 | 0.80 | MTNR1A (0.65) | MTNR1AMTNR1BALDH1A1MEN1KMT2A | |
| SCHEMBL441779 | 0.80 | MTNR1A (0.59) | MTNR1AMTNR1BALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |