Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.38 |
| ▸ | EEF2K | O00418 | 2/20 | 0.40 |
| ▸ | EEF2 | P13639 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711144 | 0.98 | KDM4E (0.41) | EEF2KEEF2KDM4ELMNACA1 | |
| Hydrochloric Acid SCHEMBL9696543 | 0.96 | KDM4E (0.43) | EEF2KEEF2KDM4ELMNACA1 | |
| Hydrochloric Acid SCHEMBL8369377 | 0.79 | TAAR1 (0.36) | KDM4EALDH1A1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL5069465 | 0.77 | L3MBTL1 (0.37) | RAB9AMEN1KMT2ASMN1; SMN2NPC1 | |
| Iodide SCHEMBL28519463 | 0.76 | LMNA (0.40) | EEF2KEEF2KDM4ELMNACA1 | |
| SCHEMBL3408449 | 0.76 | CA1 (0.46) | CA1CA2ALDH1A1 | |
| SCHEMBL14237545 | 0.76 | TAAR1 (0.44) | CA1CA2RAB9AACHENPC1 | |
| Hydrochloric Acid SCHEMBL20191168 | 0.75 | TP53 (0.43) | EEF2KEEF2KDM4ELMNACA1 | |
| Hydrochloric Acid SCHEMBL15550110 | 0.75 | CA1 (0.48) | CA1CA2ALDH1A1 | |
| Water SCHEMBL18281526 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006126861-A9 | SOLID-STATE ELECTROLYTE COMPOSITION CONTAINING LIQUID CRYSTAL MATERIALS AND DYE-SENSITIZED SOLAR CELLS USING THEREOF | BUSAN NAT UNIVERSITY INDUSTRY (KR) | 2007-03-15 | — | — | WO | disclosed |
| WO-2006126861-A1 | SOLID-STATE ELECTROLYTE COMPOSITION CONTAINING LIQUID CRYSTAL MATERIALS AND DYE-SENSITIZED SOLAR CELLS USING THEREOF | BUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2006-11-30 | — | — | WO | disclosed |