Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 11/20 | 0.41 |
| ▸ | HTR3B | O95264 | 7/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 6/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 6/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732428 | 0.78 | POLB (0.46) | HTR3AHTR3BHTR3EHTR3DHTR3C | |
| SCHEMBL21516782 | 0.78 | F10 (0.42) | HTR3AHTR3BHTR3EHTR3DHTR3C | |
| SCHEMBL3734963 | 0.78 | F10 (0.48) | HTR3AHTR3BHTR3EHTR3DHTR3C | |
| SCHEMBL21516088 | 0.78 | HTR3B (0.40) | HTR3AHTR3BHTR3EHTR3DHTR3C | |
| SCHEMBL21516108 | 0.77 | PTGS1 (0.42) | HTR3AHTR3BHTR3EHTR3DHTR3C | |
| SCHEMBL21516593 | 0.77 | F10 (0.41) | HTR3AHTR3BHTR3EHTR3DHTR3C | |
| SCHEMBL4076536 | 0.77 | GAA (0.39) | HTR3AHTR3BHTR3EHTR3DHTR3C | |
| SCHEMBL4069418 | 0.77 | F10 (0.50) | HTR3AHTR3BHTR3EHTR3DHTR3C | |
| SCHEMBL23254033 | 0.74 | POLB (0.36) | HTR3AHTR3BHTR3EHTR3DHTR3C | |
| SCHEMBL21516106 | 0.74 | GAA (0.45) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853604-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006096444-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-09-14 | — | — | WO | disclosed |