SCHEMBL3734963

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21516088	0.86	HTR3B (0.40)	F10F2KLKB1DRD2DRD4
	SCHEMBL4885839	0.83	F10 (0.46)	F10F2KLKB1CXCR4POLB
	SCHEMBL5543916	0.78	HTR3A (0.41)	HTR3EHTR3BHTR3AHTR3DHTR3C
	SCHEMBL21516782	0.78	F10 (0.42)	F10HTR3EHTR3BHTR3AHTR3D
	SCHEMBL21516108	0.77	PTGS1 (0.42)	F10HTR3EHTR3BHTR3AHTR3D
	SCHEMBL4076536	0.77	GAA (0.39)	F10HTR3EHTR3BHTR3AHTR3D
	SCHEMBL4069418	0.77	F10 (0.50)	F10HTR3EHTR3BHTR3AHTR3D
	SCHEMBL21516106	0.76	GAA (0.45)	F10KDM4EALDH1A1JAK2JAK1
	SCHEMBL3732428	0.75	POLB (0.46)	F10HTR3EHTR3BHTR3AHTR3D
	SCHEMBL21516593	0.74	F10 (0.41)	F10DRD2DRD3HTR3EHTR3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.