Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542764 | 0.98 | TSHR (0.45) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL3170416 | 0.93 | MAPT (0.48) | PDE3BPDE3AP2RY12LTA4HTSHR | |
| SCHEMBL2446705 | 0.88 | MAPT (0.47) | LTA4HTSHRALDH1A1LMNAMAPT | |
| SCHEMBL4275826 | 0.88 | HDAC1 (0.56) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL25270797 | 0.83 | HDAC1 (0.66) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL14566050 | 0.83 | MAPT (0.56) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL839640 | 0.83 | HDAC1 (0.66) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL10944790 | 0.83 | HDAC1 (0.66) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL810018 | 0.82 | PPARD (0.53) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL21260769 | 0.82 | L3MBTL1 (0.57) | HDAC1HDAC2HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229914-B1 | COMPOSITIONS AND METHODS FOR TEMPORARILY SHAPING KERATIN-CONTAINING FIBERS | HENKEL AG & CO KGAA (DE) | 2020-07-08 | — | — | EP | disclosed |
| EP-3229762-B1 | AGENTS AND METHODS FOR THE TEMPORARY SHAPING OF KERATIN-CONTAINING FIBERS | HENKEL AG & CO KGAA (DE) | 2019-03-13 | — | — | EP | disclosed |
| EP-3229765-B1 | AGENTS AND METHODS FOR THE TEMPORARY SHAPING OF KERATIN-CONTAINING FIBERS | HENKEL AG & CO KGAA (DE) | 2019-03-13 | — | — | EP | disclosed |
| EP-2785418-B1 | SHINE-PRODUCING HAIR TREATMENT AGENT | HENKEL AG & CO KGAA (DE) | 2019-01-09 | — | — | EP | disclosed |
| EP-3229913-B1 | AGENTS AND METHODS FOR THE TEMPORARY SHAPING OF KERATIN-CONTAINING FIBERS | HENKEL AG & CO KGAA (DE) | 2019-01-02 | — | — | EP | disclosed |
| EP-2211832-B1 | HAIR PREPARATION, PARTICULARLY STYLING AGENT, CONTAINING TWO COPOLYMERS | HENKEL AG & CO KGAA (DE) | 2017-03-29 | — | — | EP | disclosed |
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-2417183-B1 | CURABLE COMPOSITION | HENKEL AG & CO KGAA (DE) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | HDAC1 322/4885HDAC2 502/4885HDAC8 993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.