SCHEMBL810018

SCHEMBL810018

COC(=O)CCCCCOc1ccc(OCC(=O)OC)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 1/20 0.53
PDE3B Q13370 2/20 0.53
PDE3A Q14432 2/20 0.53
P2RY12 Q9H244 2/20 0.53
HDAC1 Q13547 5/20 0.51
HDAC8 Q9BY41 4/20 0.51
HDAC2 Q92769 4/20 0.51
HDAC6 Q9UBN7 4/20 0.51
HDAC3 O15379 3/20 0.51
HDAC4 P56524 3/20 0.51
HDAC7 Q8WUI4 3/20 0.51
HDAC10 Q969S8 3/20 0.51
HDAC11 Q96DB2 3/20 0.51
HDAC9 Q9UKV0 3/20 0.51
HDAC5 Q9UQL6 3/20 0.51
PTGS2 P35354 1/20 0.51
GAA P10253 1/20 0.50
PLA2G4B P0C869 1/20 0.49
ALDH1A1 P00352 3/20 0.49
KMT2A Q03164 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4275826 0.93 HDAC1 (0.56) PDE3BPDE3AP2RY12HDAC1HDAC8
SCHEMBL14566050 0.88 MAPT (0.56) PPARDPDE3BPDE3AP2RY12HDAC1
SCHEMBL9159587 0.87 MEN1 (0.62) PPARDPLA2G4BALDH1A1KMT2AMEN1
SCHEMBL809948 0.87 NR5A1 (0.59) PDE3BPDE3AP2RY12HDAC1HDAC8
SCHEMBL14163893 0.87 L3MBTL1 (0.57) PDE3BPDE3AP2RY12HDAC1HDAC8
SCHEMBL21260769 0.87 L3MBTL1 (0.57) PDE3BPDE3AP2RY12HDAC1HDAC8
SCHEMBL13612294 0.87 L3MBTL1 (0.57) PDE3BPDE3AP2RY12HDAC1HDAC8
SCHEMBL13933074 0.85 HDAC1 (0.50) PDE3BPDE3AP2RY12HDAC1HDAC8
SCHEMBL14883463 0.85 HDAC1 (0.51) PDE3BPDE3AP2RY12HDAC1HDAC8
SCHEMBL3161237 0.85 HDAC1 (0.50) PDE3BPDE3AP2RY12HDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902319-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2011-03-08 US disclosed
US-7902319-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2011-03-08 US disclosed
US-7902319-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2011-03-08 US disclosed
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-05-06 US disclosed
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-05-06 US disclosed
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-05-06 US disclosed
US-7671168-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2010-03-02 US disclosed
US-7671168-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2010-03-02 US disclosed
US-7671168-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2010-03-02 US disclosed
US-20070141113-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-21 US disclosed
US-20070141113-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-21 US disclosed
US-20070141113-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM DDT, ACMSD, HPD PPARD 626/4885PDE3B 3791/4885PDE3A 3673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.