Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5544381 | 0.82 | ALDH1A1 (0.43) | APPADORA3ADORA2ATUBB4ATUBB | |
| SCHEMBL34462740 | 0.80 | TAAR1 (0.51) | TAAR1 | |
| SCHEMBL31347508 | 0.77 | TDP1 (0.45) | TAAR1MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL4832016 | 0.73 | TAAR1 (0.51) | TAAR1KMT2AALDH1A1PTGS2HPGD | |
| SCHEMBL9194437 | 0.72 | DPP4 (0.58) | APPLOXL2MEN1KMT2AALDH1A1 | |
| SCHEMBL28789839 | 0.71 | POLB (0.41) | APPLOXL2MEN1KMT2AALDH1A1 | |
| SCHEMBL4829716 | 0.71 | KDM4E (0.51) | TAAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13076481 | 0.71 | KDM4E (0.51) | TAAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8504212 | 0.70 | TAAR1 (0.59) | TAAR1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL7916537 | 0.70 | TAAR1 (0.50) | TAAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112523-A1 | Ligands for 17i as modulators of orthopox viruses and methods for discovery thereof | TRANSTECH PHAMA,INC. | 2007-05-17 | — | — | US | disclosed |