Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.42 |
| ▸ | TUBB | P07437 | 3/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5544388 | 0.82 | APP (0.42) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL4832008 | 0.74 | TDP1 (0.48) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL4829703 | 0.72 | LMNA (0.49) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL23675461 | 0.72 | POLB (0.44) | ALDH1A1SMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL11291420 | 0.71 | NR1H4 (0.55) | ALDH1A1KMT2AHPGDTDP1 | |
| SCHEMBL4940053 | 0.70 | NR1H4 (0.46) | ALDH1A1HPGDGAA | |
| SCHEMBL1032325 | 0.70 | CA12 (0.50) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL9890762 | 0.69 | PTGDR2 (0.54) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL4685087 | 0.69 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL29639810 | 0.69 | ALDH1A1 (0.41) | ALDH1A1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112523-A1 | Ligands for 17i as modulators of orthopox viruses and methods for discovery thereof | TRANSTECH PHAMA,INC. | 2007-05-17 | — | — | US | disclosed |