SCHEMBL5544519

SCHEMBL5544519

O=C1Oc2ccccc2C1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.68
MAOB P27338 1/20 0.68
ATM Q13315 2/20 0.47
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
CYP2C9 P11712 2/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
USP2 O75604 1/20 0.41
GRM1 Q13255 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29419966 0.81 MAOA (1.00) MAOAMAOBATMHDAC3HDAC4
SCHEMBL521775 0.81 MAOA (1.00) MAOAMAOBATMHDAC3HDAC4
SCHEMBL28681589 0.79 MAOA (0.95) MAOAMAOBATMHDAC3HDAC4
SCHEMBL5713260 0.78 MAOA (0.61) MAOAMAOBATMHDAC3HDAC4
SCHEMBL8869259 0.78 MAOA (0.61) MAOAMAOBATMHDAC3HDAC4
SCHEMBL2721424 0.77 MAOA (0.74) MAOAMAOBATMHDAC3HDAC4
SCHEMBL28594018 0.77 TDP1 (0.46) MAOAMAOBCYP2C9MEN1KMT2A
SCHEMBL20785354 0.76 MAOA (0.46) MAOAMAOBATMHDAC3HDAC4
SCHEMBL20785353 0.76 MAOA (0.46) MAOAMAOBATMHDAC3HDAC4
SCHEMBL20169271 0.76 MAOA (0.46) MAOAMAOBATMHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106807275-A A kind of heavy-metal contaminated soil treatment agent mixing plant and its method of work 徐州工程学院 2017-06-09 CN claimed
EP-0630364-B1 HYDROXY DERIVATIVES OF CYCLOHEXADIENE ZENECA LTD (GB) 1997-08-27 EP claimed
WO-1993017994-A1 HYDROXY DERIVATIVES OF CYCLOHEXADIENE ZENECA LIMITED (GB) 1993-09-16 WO claimed
JP-7082261-A None JP disclosed
JP-11080563-A None JP disclosed
EP-4688936-A1 THERMOPLASTIC POLYMER COMPOSITIONS CONTAINING STABILISER MIXTURES BASF SE (DE) 2026-02-11 EP disclosed
CN-118724882-B Mitochondrial DNA fluorescent probe, preparation method and biological imaging application thereof 山东大学 2025-02-25 CN disclosed
US-12162852-B2 Lactone compound FUJIFILM CORPORATION (JP) 2024-12-10 US disclosed
WO-2024208842-A1 THERMOPLASTIC POLYMER COMPOSITIONS CONTAINING STABILISER MIXTURES BASF SE (DE) 2024-10-10 WO disclosed
CN-118724882-A Mitochondrial DNA fluorescent probe, preparation method and biological imaging application thereof 山东大学 2024-10-01 CN disclosed
WO-2024053468-A1 CATALYTIC REACTION METHOD, METHOD FOR PRODUCING ORGANIC COMPOUND, AND CATALYST COMPOSITION 日東電工株式会社 2024-03-14 WO disclosed
WO-1995002403-A1 5-LIPOXYGENASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1995-01-26 WO disclosed
EP-0630364-A1 HYDROXY DERIVATIVES OF CYCLOHEXADIENE. ZENECA LTD (GB) 1994-12-28 EP disclosed
WO-1993017994-A1 HYDROXY DERIVATIVES OF CYCLOHEXADIENE ZENECA LIMITED (GB) 1993-09-16 WO disclosed
EP-0522000-A1 5-LIPOXYGENASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1993-01-13 EP disclosed
US-5149703-A Anti-asthma, allergen and inflammatory agents, cyctoprotective agents MERCK FROSST CANADA, INC. (CA) 1992-09-22 US disclosed
WO-1991014674-A2 5-LIPOXYGENASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1991-10-03 WO disclosed
US-4837293-A Linear bisphenol epoxy polymers containing cyano groups THE DOW CHEMICAL COMPANY (US) 1989-06-06 US disclosed
US-4464354-A (3,4-c)-Pyrido psoralens, process of preparation, application in cosmetology and therapeutics, and cosmetological and pharmaceutical composition with them INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 1984-08-07 US disclosed
EP-0088024-A1 Pyrido(3,4-c)psoralenes, preparation, use in cosmetology and in medicine and compositions containing them INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 1983-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12162852-B2 Lactone compound MRPS22, YWHAZ, RPLP1 MAOA 4372/4885MAOB 3525/4885ATM 4704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.