Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.60 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.60 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.60 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.60 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.60 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.60 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.60 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.60 |
| ▸ | CCR2 | P41597 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | HPGDS | O60760 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5536458 | 0.86 | KMT2A (0.58) | FAAHPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL5537723 | 0.85 | CA1 (0.56) | KCNH2MAPTLMNAKMT2A | |
| SCHEMBL5535039 | 0.84 | ACHE (0.66) | TRPV1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL5542346 | 0.83 | FAAH (0.59) | FAAHCCR2KCNH2MAPTTRPV1 | |
| SCHEMBL5546599 | 0.83 | NPC1 (0.58) | FAAHMAPT | |
| SCHEMBL5541740 | 0.83 | FAAH (0.65) | FAAHMAPTNPSR1 | |
| SCHEMBL5544609 | 0.82 | FAAH (0.60) | FAAHPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL31664725 | 0.81 | FAAH (0.59) | FAAHPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL5546039 | 0.80 | MAPT (0.70) | FAAHPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL15134839 | 0.80 | EPHX2 (0.69) | FAAHPRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | FAAH 4363/4885PRKAB2 3290/4885PRKAG1 3704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.