SCHEMBL5544730

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5547928	0.88	CHRM1 (0.41)	CHRM1HTR2AMCHR1DHFRAOC3
	SCHEMBL13261441	0.80	MAPT (0.50)	CHRM1HTR2AMCHR1DHFRMAPT
	SCHEMBL28289217	0.80	CHRM1 (0.46)	CHRM1HTR2AMCHR1DHFRMAPT
	SCHEMBL5536973	0.79	CA12 (0.41)	MAPTAOC3
	SCHEMBL2091801	0.79	CHKA (0.43)	CHRM1HTR2AMCHR1AOC3ALDH1A1
	SCHEMBL17351162	0.78	KCNH2 (0.51)	CHRM1HTR2AMCHR1MAPT
	SCHEMBL5542642	0.78	HTR7 (0.52)	MAPTAOC3ALDH1A1KDM4E
	SCHEMBL5536531	0.77	RPS6KA2 (0.43)	MAPTAOC3ALDH1A1KDM4EHPGD
	SCHEMBL6859648	0.77	CHRM1 (0.42)	CHRM1HTR2AMCHR1DHFRMAPT
	SCHEMBL5539693	0.76	KIF11 (0.39)	CHRM1DHFRMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.