SCHEMBL5544765

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12952779	0.91	PTGES (0.55)	NR1H4RAB9AMEN1KMT2APTGES
	SCHEMBL2096288	0.84	MTOR (0.46)	MEN1KMT2ATMEM97SIGMAR1NR1H2
	SCHEMBL305634	0.82	TSHR (0.50)	RAB9ALMNACNR2NPC1TSHR
	SCHEMBL2093213	0.81	CYP2C19 (0.59)	LMNACNR2TSHRALDH1A1CYP2C19
	SCHEMBL5541695	0.81	TP53 (0.50)	MEN1KMT2ALMNACNR2TSHR
	SCHEMBL16863769	0.79	ALDH1A1 (0.51)	RAB9AMEN1KMT2ALMNACNR2
	SCHEMBL2085586	0.78	CNR2 (0.47)	CNR2L3MBTL1
	SCHEMBL2091210	0.78	TSHR (0.43)	TMEM97SIGMAR1CNR2TSHRALDH1A1
	SCHEMBL2094150	0.78	CNR2 (0.47)	MEN1KMT2ATMEM97SIGMAR1CNR2
	SCHEMBL2096018	0.78	HTR2A (0.40)	MEN1KMT2ALMNACNR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.