Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301401 | 0.83 | AR (0.40) | ARCES2CRHR1MAPTALDH1A1 | |
| SCHEMBL26020399 | 0.82 | CES2 (0.45) | ARCES2CRHR1MAPTALDH1A1 | |
| SCHEMBL1110884 | 0.81 | CFTR (0.48) | ARCES2MAPTALDH1A1HPGD | |
| SCHEMBL26440666 | 0.81 | AR (0.41) | ARCES2CRHR1MAPTALDH1A1 | |
| SCHEMBL4620600 | 0.77 | CES2 (0.46) | CES2MAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL24177167 | 0.75 | CES2 (0.47) | CES2MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL29789763 | 0.75 | CES2 (0.47) | CES2KMT2AATMPARP1DGAT1 | |
| SCHEMBL5342821 | 0.75 | GPR52 (0.47) | MAPTALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL1032909 | 0.75 | CES2 (0.47) | CES2KMT2AATMPARP1DGAT1 | |
| SCHEMBL29789661 | 0.75 | CES2 (0.47) | CES2MAPTALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |