SCHEMBL5545798

SCHEMBL5545798

O=C(c1ccc(-c2ccccc2)cc1)c1cc(Cl)ccc1Cl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
SERPINE1 P05121 2/20 0.55
ALDH1A1 P00352 3/20 0.55
TP53 P04637 1/20 0.55
ATM Q13315 2/20 0.54
CDC25B P30305 1/20 0.54
SRD5A2 P31213 2/20 0.54
NPSR1 Q6W5P4 2/20 0.54
KDM4E B2RXH2 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
MAPT P10636 2/20 0.54
LMNA P02545 1/20 0.54
NR4A1 P22736 1/20 0.53
CNR2 P34972 1/20 0.50
MITF O75030 1/20 0.49
HSP90AA1 P07900 1/20 0.49
HTT P42858 1/20 0.49
TLR9 Q9NR96 1/20 0.49
RECQL P46063 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31474388 1.00 MEN1 (0.57) MEN1KMT2ASERPINE1ALDH1A1TP53
SCHEMBL31474389 1.00 MEN1 (0.57) MEN1KMT2ASERPINE1ALDH1A1TP53
SCHEMBL12122750 0.91 SERPINE1 (0.51) MEN1KMT2ASERPINE1ALDH1A1TP53
SCHEMBL13309938 0.90 CNR2 (0.60) SERPINE1ALDH1A1TP53ATMSRD5A2
SCHEMBL13309942 0.90 CNR2 (0.60) SERPINE1ALDH1A1TP53ATMSRD5A2
SCHEMBL29612638 0.90 ALDH1A1 (0.63) MEN1KMT2ASERPINE1ALDH1A1TP53
SCHEMBL230930 0.90 ALDH1A1 (0.63) MEN1KMT2ASERPINE1ALDH1A1TP53
SCHEMBL7466437 0.86 ALDH1A1 (0.61) MEN1KMT2AALDH1A1TP53SRD5A2
SCHEMBL17134428 0.83 ALDH1A1 (0.57) SERPINE1ALDH1A1TP53ATMSRD5A2
SCHEMBL596448 0.83 SERPINE1 (0.58) MEN1KMT2ASERPINE1ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8058365-B2 Proton conducting membrane and process for producing the same JSR CORPORATION (JP) 2011-11-15 US disclosed
US-8058365-B2 Proton conducting membrane and process for producing the same JSR CORPORATION (JP) 2011-11-15 US disclosed
US-8039165-B2 Proton conductive membrane comprising a copolymer JSR CORPORATION (JP) 2011-10-18 US disclosed
US-8039165-B2 Proton conductive membrane comprising a copolymer JSR CORPORATION (JP) 2011-10-18 US disclosed
US-7993792-B2 Polymer blocks for PEM applications GM Global Technology Operations LLC (US) 2011-08-09 US disclosed
US-7993792-B2 Polymer blocks for PEM applications GM Global Technology Operations LLC (US) 2011-08-09 US disclosed
US-20090040690-A1 Electrochemical capacitor JSR CORPORATION (JP) 2009-02-12 US disclosed
US-20090040690-A1 Electrochemical capacitor JSR CORPORATION (JP) 2009-02-12 US disclosed
US-7449132-B2 Proton conductive composition and proton conductive membrane JSR CORPORATION (JP) 2008-11-11 US disclosed
US-7449132-B2 Proton conductive composition and proton conductive membrane JSR CORPORATION (JP) 2008-11-11 US disclosed
US-7396607-B2 Manufacturing process for membrane-electrode assemblies JSR CORPORATION (JP) 2008-07-08 US disclosed
US-20080027151-A1 Polymer Blocks For PEM Applications GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2008-01-31 US disclosed
US-20080027151-A1 Polymer Blocks For PEM Applications GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2008-01-31 US disclosed
US-20070117872-A1 Proton conducting membrane and process for producing the same JSR CORPORATION (JP) 2007-05-24 US disclosed
US-20070117872-A1 Proton conducting membrane and process for producing the same JSR CORPORATION (JP) 2007-05-24 US disclosed
US-20070111071-A1 Proton conducting membrane JSR CORPORATION (JP) 2007-05-17 US disclosed
US-20070111071-A1 Proton conducting membrane JSR CORPORATION (JP) 2007-05-17 US disclosed
US-20070020500-A1 Membrane-electrode structure for solid polymer fuel cell and solid polymer fuel cell HONDA MOTOR CO., LTD 2007-01-25 US disclosed
US-20070020500-A1 Membrane-electrode structure for solid polymer fuel cell and solid polymer fuel cell HONDA MOTOR CO., LTD 2007-01-25 US disclosed
US-20070015025-A1 Membrane electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. 2007-01-18 US disclosed