Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BCL3 | P20749 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14511031 | 0.87 | KDM4E (0.59) | KDM4EALDH1A1LMNARAD52TSHR | |
| SCHEMBL5546706 | 0.86 | KDM4E (0.53) | KDM4EALDH1A1LMNARAD52TSHR | |
| SCHEMBL5538459 | 0.85 | KDM4E (0.54) | KDM4EALDH1A1LMNARAD52TSHR | |
| SCHEMBL5545450 | 0.83 | KDM4E (0.52) | KDM4EALDH1A1LMNARAD52TSHR | |
| SCHEMBL5545347 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1LMNARAD52TSHR | |
| SCHEMBL5545335 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1LMNARAD52TSHR | |
| SCHEMBL5545421 | 0.78 | PARP1 (0.47) | KDM4EALDH1A1LMNARAD52TSHR | |
| SCHEMBL5540835 | 0.75 | KDM4E (0.54) | KDM4EALDH1A1LMNAPARP1HSD17B10 | |
| SCHEMBL5545293 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1LMNAPARP1TP53 | |
| SCHEMBL5545648 | 0.72 | ALDH1A1 (0.48) | KDM4EALDH1A1LMNATSHRPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070124152-A1 | Hiv Integrase Inhibitors | GLAXOSMITHKLINE LLC | 2007-05-31 | — | — | US | claimed |