SCHEMBL5545335

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14511031	0.91	KDM4E (0.59)	KDM4EALDH1A1KMT2AHSD17B10ALOX15
	SCHEMBL5540835	0.89	KDM4E (0.54)	KDM4EALDH1A1KMT2AHSD17B10ALOX15
	SCHEMBL5545293	0.88	KDM4E (0.55)	KDM4EALDH1A1KMT2AHSD17B10ALOX15
	SCHEMBL5545450	0.87	KDM4E (0.52)	KDM4EALDH1A1LMNARAD52TSHR
	SCHEMBL5545648	0.85	ALDH1A1 (0.48)	KDM4EALDH1A1KMT2AHSD17B10LMNA
	SCHEMBL6061942	0.85	TDP1 (0.46)	KDM4EALDH1A1KMT2AHSD17B10ALOX15
	SCHEMBL15163541	0.84	TDP1 (0.48)	KDM4EALDH1A1KMT2AHSD17B10ALOX15
	SCHEMBL15163542	0.83	TDP1 (0.48)	KDM4EALDH1A1KMT2AHSD17B10ALOX15
	SCHEMBL5538646	0.83	TDP1 (0.47)	KDM4EKMT2AHSD17B10ALOX15LMNA
	SCHEMBL5546031	0.83	TDP1 (0.52)	KDM4EALDH1A1KMT2AHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.