Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1692572 | 0.80 | HSD17B10 (0.39) | — | |
| SCHEMBL501616 | 0.80 | MEN1 (0.39) | — | |
| SCHEMBL263592 | 0.77 | GAA (0.42) | NOS1NOS2 | |
| SCHEMBL7127295 | 0.77 | — | — | |
| SCHEMBL3824241 | 0.77 | — | — | |
| SCHEMBL241363 | 0.77 | TP53 (0.37) | NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL7214713 | 0.75 | GAA (0.44) | NOS1NOS2 | |
| SCHEMBL118587 | 0.75 | KDM4E (0.53) | — | |
| SCHEMBL3737872 | 0.74 | — | — | |
| SCHEMBL241224 | 0.74 | CNR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1830858-A2 | 3, 6-BICYCLOLIDES | Enanta Pharmaceuticals, Inc. (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006063039-A2 | 3, 6-BICYCLOLIDES | ENANTA PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | disclosed |