Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102945 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL31229543 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL15161494 | 0.85 | MEN1 (0.37) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6099721 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL13147479 | 0.80 | IAPP (0.37) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL1249952 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL117253 | 0.79 | SMN1; SMN2 (0.48) | ALDH1A1MAPTHSD17B10NFKB1LMNA | |
| SCHEMBL1692572 | 0.79 | HSD17B10 (0.39) | HSD17B10CA2 | |
| SCHEMBL31262817 | 0.79 | HSD17B10 (0.39) | HSD17B10CA2 | |
| Phenylacetic Acid SCHEMBL27559287 | 0.79 | AKR1B1 (0.55) | ALDH1A1MAPTHPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702567-B2 | Moisture curable organopolysiloxane composition and electric/electronic apparatus | DOW SILICONES CORPORATION (US) | 2023-07-18 | — | — | US | disclosed |
| EP-3103842-B1 | CURABLE SILICONE COMPOSITION, CURED OBJECT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE | DOW TORAY CO LTD (JP) | 2023-01-11 | — | — | EP | disclosed |
| EP-3802717-B1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION AND ELECTRIC/ELECTRONIC APPARATUS | DOW SILICONES CORP (US) | 2022-12-21 | — | — | EP | disclosed |
| US-20220363667-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | NIPPON CHEMIPHAR CO., LTD. (JP) | 2022-11-17 | — | — | US | disclosed |
| US-20220226299-A1 | USE OF T-TYPE CALCIUM CHANNEL BLOCKER FOR TREATING PRURITUS | NIPPON CHEMIPHAR CO., LTD. (JP) | 2022-07-21 | — | — | US | disclosed |
| EP-3039079-B1 | CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE | DDP SPECIALTY ELECTRONIC MAT US 9 LLC (US) | 2022-05-18 | — | — | EP | disclosed |
| EP-3950059-A1 | USE OF T-TYPE CALCIUM CHANNEL BLOCKER FOR TREATING PRURITUS | Nippon Chemiphar Co., Ltd. (JP) | 2022-02-09 | — | — | EP | disclosed |
| CN-112088195-B | Moisture-curable organopolysiloxane composition and electrical/electronic device | 美国陶氏有机硅公司 | 2021-09-28 | — | — | CN | disclosed |
| US-20210238444-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION AND ELECTRIC/ELECTRONIC APPARATUS | DOW SILICONES CORPORATION | 2021-08-05 | — | — | US | disclosed |
| EP-3825303-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | Nippon Chemiphar Co., Ltd. (JP) | 2021-05-26 | — | — | EP | disclosed |
| US-8822476-B2 | Piperidine and piperazine derivatives as autotaxin inhibitors | MERCK PATENT GMBH (DE) | 2014-09-02 | — | — | US | disclosed |
| WO-2014126265-A1 | CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE | DOW CORNING TORAY CO., LTD. (JP) | 2014-08-21 | — | — | WO | disclosed |
| US-20120059016-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES AS AUTOTAXIN INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-03-08 | — | — | US | disclosed |
| US-20120059016-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES AS AUTOTAXIN INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-03-08 | — | — | US | disclosed |
| US-7112553-B1 | Pesticidal indazole or benzotriazole derivatives | SYNGENTA LIMITED (GB) | 2006-09-26 | — | — | US | disclosed |
| EP-1171437-B1 | PESTICIDAL INDAZOLE OR BENZOTRIAZOLE DERIVATIVES | SYNGENTA LTD (GB) | 2003-10-08 | — | — | EP | disclosed |
| EP-1171437-A1 | PESTICIDAL INDAZOLE OR BENZOTRIAZOLE DERIVATIVES | Syngenta Limited (GB) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000063207-A1 | PESTICIDAL INDAZOLE OR BENZOTRIAZOLE DERIVATIVES | SYNGENTA LIMITED (GB) | 2000-10-26 | — | — | WO | disclosed |
| EP-0174135-A2 | Heat-developable color light-sensitive material | KONICA CORPORATION (JP) | 1986-03-12 | — | — | EP | disclosed |
| US-4522785-A | Dialkylaminomethyl aromatic triazoles as corrosion inhibitors | THE SHERWIN-WILLIAMS COMPANY (US) | 1985-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059016-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES AS AUTOTAXIN INHIBITORS | ENPP2, PLA2G12A, PLA2G2E | KDM4E 1526/4885ALDH1A1 2635/4885MAPT 3630/4885 |
| US-20220363667-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | CACNA1I, CACNA1G, CACNA1H | KDM4E 3937/4885ALDH1A1 3434/4885MAPT 304/4885 |
| US-20220226299-A1 | USE OF T-TYPE CALCIUM CHANNEL BLOCKER FOR TREATING PRURITUS | TRPV3, CACNA1G, TRPV2 | KDM4E 3799/4885ALDH1A1 3671/4885MAPT 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.