Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17827971 | 0.81 | UHRF1 (0.43) | UHRF1CCR1CCR5CCR8KMT2A | |
| SCHEMBL14670941 | 0.81 | UHRF1 (0.46) | UHRF1CCR1CCR5CCR8KMT2A | |
| SCHEMBL20342497 | 0.81 | UHRF1 (0.46) | UHRF1CCR1CCR5CCR8KMT2A | |
| SCHEMBL13991779 | 0.81 | UHRF1 (0.46) | UHRF1CCR1CCR5CCR8KMT2A | |
| SCHEMBL643383 | 0.79 | UHRF1 (0.48) | UHRF1CCR1CCR5CCR8KMT2A | |
| SCHEMBL26916427 | 0.79 | UHRF1 (0.48) | UHRF1CCR1CCR5CCR8KMT2A | |
| SCHEMBL17828007 | 0.78 | UHRF1 (0.43) | UHRF1CCR1CCR5CCR8KMT2A | |
| SCHEMBL18672385 | 0.76 | UHRF1 (0.42) | UHRF1CCR1CCR5CCR8KMT2A | |
| SCHEMBL20116282 | 0.76 | UHRF1 (0.45) | UHRF1CCR1CCR5CCR8KMT2A | |
| SCHEMBL29453940 | 0.74 | UHRF1 (0.52) | UHRF1CCR1CCR5CCR8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176314-B2 | IkB kinases (IKK) enzyme inhibitors, a imidazole-5-yl-quinoline derivatives compounds | AMGEN, INC. (US) | 2007-02-13 | — | — | US | disclosed |
| US-20030181472-A1 | Inflammation modulators | TULARIK INC. | 2003-09-25 | — | — | US | disclosed |
| WO-2003048152-A2 | INFLAMMATION MODULATORS | TULARIK INC. (US) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181472-A1 | Inflammation modulators | NFATC1, NFKBIA, RELA | UHRF1 2277/4885CCR1 205/4885CCR5 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.