Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 3/20 | 0.34 |
| ▸ | CDK8 | P49336 | 3/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.33 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.33 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16247856 | 0.82 | SLC22A12 (0.50) | SLC22A12MEN1KMT2AKDM5AKDM5B | |
| SCHEMBL16247942 | 0.79 | SLC22A12 (0.50) | SLC22A12MEN1KMT2AKDM5AKDM5B | |
| SCHEMBL16247960 | 0.79 | SLC22A12 (0.56) | SLC22A12MEN1KMT2AKDM5AKDM5B | |
| SCHEMBL3400822 | 0.74 | SLC22A12 (0.46) | SLC22A12CCR1CCR5CCR8IDO1 | |
| SCHEMBL20125489 | 0.72 | KDM5B (0.63) | SLC22A12KDM5AKDM5B | |
| SCHEMBL4798760 | 0.72 | MEN1 (0.44) | SLC22A12MEN1KMT2ACDK1 | |
| SCHEMBL663301 | 0.71 | MEN1 (0.47) | SLC22A12MEN1KMT2ANPSR1CDK1 | |
| SCHEMBL11822451 | 0.71 | KMT2A (0.43) | SLC22A12MEN1KMT2AL3MBTL1CDK1 | |
| SCHEMBL24956766 | 0.68 | HTR1A (0.51) | SLC22A12MEN1KMT2ACCR1CCR5 | |
| SCHEMBL3252945 | 0.68 | NR4A2 (0.58) | MEN1KMT2ACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176314-B2 | IkB kinases (IKK) enzyme inhibitors, a imidazole-5-yl-quinoline derivatives compounds | AMGEN, INC. (US) | 2007-02-13 | — | — | US | disclosed |
| US-20030181472-A1 | Inflammation modulators | TULARIK INC. | 2003-09-25 | — | — | US | disclosed |
| WO-2003048152-A2 | INFLAMMATION MODULATORS | TULARIK INC. (US) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181472-A1 | Inflammation modulators | NFATC1, NFKBIA, RELA | SLC22A12 4446/4885MEN1 4672/4885KMT2A 3709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.