Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | SDCBP | O00560 | 1/20 | 0.39 |
| ▸ | SDC2 | P34741 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10597373 | 0.79 | ALDH1A1 (0.52) | SMN1; SMN2HSP90AA1KCNH2L3MBTL1MAOA | |
| SCHEMBL7009510 | 0.79 | CA2 (0.46) | HSP90AA1KCNH2RAB9ANPC1NFKB1 | |
| SCHEMBL7514361 | 0.79 | ALDH1A1 (0.49) | SMN1; SMN2L3MBTL1RAB9ANPC1ALDH1A1 | |
| SCHEMBL5542119 | 0.79 | KDM4E (0.47) | L3MBTL1RAB9ANPC1POLBPKM | |
| SCHEMBL5542701 | 0.79 | ALDH1A1 (0.41) | SMN1; SMN2MAOARAB9ANPC1POLB | |
| SCHEMBL17030474 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2HSP90AA1KCNH2L3MBTL1MAOA | |
| SCHEMBL949802 | 0.78 | ALDH1A1 (0.61) | SMN1; SMN2RAB9ANPC1CASP3SENP8 | |
| SCHEMBL10595686 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2HSP90AA1KCNH2L3MBTL1MAOA | |
| SCHEMBL9621312 | 0.75 | HRH3 (0.45) | CRBN | |
| SCHEMBL15945534 | 0.75 | DAO (0.42) | ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| EP-0323915-B1 | BETA-HYDROXYKETONE AND ITS PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-5101076-A | β-hydroxyketone and its production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-03-31 | — | — | US | disclosed |
| US-5041679-A | Beta-hydroxyketone and its production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0323915-A1 | Beta-hydroxyketone and its production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | SMN1; SMN2 3985/4885HSP90AA1 2426/4885KCNH2 3503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.