SCHEMBL5546420

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5543154	0.89	TAAR1 (0.50)	TAAR1AGERHTR2AMEN1MAPT
	SCHEMBL5539316	0.84	TAAR1 (0.44)	TAAR1HTR2ACHRM1MCHR1MAPT
	SCHEMBL5542054	0.83	SIGMAR1 (0.42)	SIGMAR1HTR2ACHRM1MCHR1MAPT
	SCHEMBL5537278	0.83	CHRM1 (0.52)	TAAR1HTR2AHDAC3CHRM1MCHR1
	SCHEMBL5545933	0.83	HPGD (0.42)	MAPTKMT2ANPC1GAARAB9A
	SCHEMBL5536505	0.83	MAPT (0.49)	TAAR1HTR2ACHRM1MCHR1MEN1
	SCHEMBL5548437	0.83	L3MBTL1 (0.40)	TAAR1SIGMAR1HTR2ACHRM1MCHR1
	SCHEMBL4827710	0.82	L3MBTL1 (0.55)	SIGMAR1MEN1MAPTKMT2AL3MBTL1
	SCHEMBL5536321	0.81	SPHK1 (0.46)	HTR2ACHRM1ALDH1A1
	SCHEMBL5537341	0.81	TAAR1 (0.49)	TAAR1SIGMAR1MAPTL3MBTL1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.