Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17231059 | 0.94 | LMNA (0.60) | LMNAMAPTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9702630 | 0.92 | LMNA (0.54) | LMNAMAPTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9774307 | 0.87 | KMT2A (0.51) | LMNAMAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL17530460 | 0.86 | LMNA (0.50) | LMNAMAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL27731656 | 0.86 | LMNA (0.66) | LMNAMAPTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8154526 | 0.85 | LMNA (0.74) | LMNAMAPTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5163351 | 0.84 | LMNA (0.56) | LMNAMAPTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL17530915 | 0.84 | TSHR (0.66) | LMNAMAPTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8493622 | 0.84 | LMNA (0.56) | LMNAMAPTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8080660 | 0.83 | MEN1 (0.57) | LMNAMAPTKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160319322-A1 | PATHOGEN DETECTION | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2016-11-03 | — | — | US | disclosed |
| US-20160221992-A1 | DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2016-08-04 | — | — | US | disclosed |
| US-7288593-B2 | Enhanced oxygen barrier performance from modification of ethylene vinyl alcohol copolymers (EVOH) | CRYOVAC, INC. (US) | 2007-10-30 | — | — | US | disclosed |
| US-20060251841-A1 | Enhanced oxygen barrier performance from modification of ethylene vinyl alcohol copolymers (EVOH) | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2006-11-09 | — | — | US | disclosed |
| US-6143197-A | MIXING A COPOLYMER OF ETHYLENE AND A VINYL UNSATURATED ALICYCLIC MONOMER, A TRANSITION METAL CATALYST, SHAPING TO FORM A PACKAGING MATERIAL OR FILM, EXPOSING THE FORMED FILM OR PACKAGING MATERIAL TO ACTINIC OR ELECTRON BEAM RADIATION | CRYOVAC, INC. (US) | 2000-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221992-A1 | DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF | MSR1, CD74, CD4 | LMNA 2564/4885MAPT 1832/4885L3MBTL1 3264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.