Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5546782 | 0.92 | LMNA (0.56) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL9374466 | 0.90 | LMNA (0.55) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL17231059 | 0.89 | LMNA (0.60) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL9528491 | 0.89 | KDM4E (0.53) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL9373776 | 0.88 | LMNA (0.47) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL9376948 | 0.87 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL810987 | 0.87 | KMT2A (0.51) | LMNAALDH1A1KDM4EMAPTCNR1 | |
| SCHEMBL27731675 | 0.85 | LMNA (0.59) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL3135517 | 0.84 | LMNA (0.74) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL9374255 | 0.84 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |