SCHEMBL554707

SCHEMBL554707

CS(=O)(=O)C[O]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14393323 0.76
SCHEMBL10629 0.74
SCHEMBL55956 0.70
SCHEMBL597046 0.70 NLRP3 (0.50)
Ammonia Solution, Strong SCHEMBL7538869 0.70
SCHEMBL65785 0.70
SCHEMBL1728092 0.67
SCHEMBL9149938 0.67
SCHEMBL11836433 0.67
SCHEMBL124953 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111747952-A Imidazoquinolinones and their use as ATM kinase inhibitors 默克专利股份公司 2020-10-09 CN claimed
CN-111689963-A Imidazoquinolinones and their use as ATM kinase inhibitors 默克专利股份公司 2020-09-22 CN claimed
US-20180072715-A1 IMIDAZOLONYLQUINOLINES AND THE USE THEREOF AS ATM KINASE INHIBITORS MERCK PATENT GMBH (DE) 2018-03-15 US claimed
EP-3277681-A1 IMIDAZOLONYL QUINOLINES AND USE THEREOF AS ATM KINASE INHIBITORS Merck Patent GmbH (DE) 2018-02-07 EP claimed
WO-2016155884-A1 IMIDAZOLONYL QUINOLINES AND USE THEREOF AS ATM KINASE INHIBITORS MERCK PATENT GMBH (DE) 2016-10-06 WO claimed
US-20160200734-A1 CARBOXYLIC ACID COMPOUNDS IN TREATMENT OF DIABETES MELLITUS KANG, XINSHAN (CN) 2016-07-14 US claimed
EP-3036237-A1 CARBOXYLIC ACID COMPOUNDS IN TREATMENT OF DIABETES MELLITUS Fujian Haixi Pharmaceuticals Co. Ltd (CN) 2016-06-29 EP claimed
WO-2016058928-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2016-04-21 WO claimed
WO-2015024526-A1 CARBOXYLIC ACID COMPOUNDS IN TREATMENT OF DIABETES MELLITUS FUJIAN HAIXI PHARMACEUTICALS CO., LTD (CN) 2015-02-26 WO claimed
EP-2298769-B1 Xanthin derivatives, their production and utilisation as medicine BOEHRINGER INGELHEIM PHARMA (DE) 2013-10-30 EP claimed
US-20050197328-A1 Imidazopyridine derivatives as kinase inhibitors GLAXO GROUP LIMITED (GB) 2005-09-08 US claimed
US-20050038016-A1 Arylamine-substituted quinazolinone compounds useful as alpha 1A/B adrenergic receptor antagonists ROCHE PALO ALTO LLC 2005-02-17 US claimed
EP-1490367-A1 IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS GLAXO GROUP LIMITED (GB) 2004-12-29 EP claimed
US-20040087587-A1 Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2004-05-06 US claimed
US-20040077645-A1 Dipeptidyl aminopeptidase inhibitors; diabetes mellitus, arthritis, obesity, allograft transplantation and osteoporosis treatment BOEHRINGER INGELHEIM PHARMA GMBH & CO KG (DE) 2004-04-22 US claimed
EP-1368349-A1 XANTHINE DERIVATIVE, PRODUCTION AND USE THEREOF AS A MEDICAMENT Boehringer Ingelheim Pharma GmbH & Co.KG (DE) 2003-12-10 EP claimed
WO-2003080610-A1 IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS GLAXO GROUP LIMITED (GB) 2003-10-02 WO claimed
US-20020198205-A1 Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-12-26 US claimed
WO-2002068420-A1 XANTHINE DERIVATIVE, PRODUCTION AND USE THEREOF AS A MEDICAMENT BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-09-06 WO claimed
US-6268310-B1 CONTROLLING WEEDS NIPPON SODA CO., LTD. (JP) 2001-07-31 US claimed