⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10715740 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL7776525 | 0.74 | — | — | |
| SCHEMBL20252803 | 0.72 | — | — | |
| SCHEMBL18040326 | 0.71 | — | — | |
| SCHEMBL10716491 | 0.70 | — | — | |
| SCHEMBL5495241 | 0.69 | TSHR (0.40) | — | |
| SCHEMBL6051987 | 0.69 | — | — | |
| SCHEMBL20464014 | 0.65 | THRB (0.35) | — | |
| SCHEMBL3892375 | 0.65 | — | — | |
| SCHEMBL2698450 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-4675451-A | Process for the preparation of 2-alkyl-1,4-butanedial | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1987-06-23 | — | — | US | disclosed |
| EP-0191935-A1 | Process for the production of 2-alkyl-1,4-butane dial | Degussa Aktiengesellschaft (DE) | 1986-08-27 | — | — | EP | disclosed |