Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2915787 | 0.89 | MAOA (0.58) | MEN1KMT2ATDP1MAOACHRM2 | |
| Hydrochloric Acid SCHEMBL28667301 | 0.85 | MAOA (0.62) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL3193069 | 0.82 | MEN1 (0.53) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL3168512 | 0.81 | MEN1 (0.50) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL22306916 | 0.80 | DRD4 (0.51) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL14361919 | 0.80 | MEN1 (0.50) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL5784665 | 0.79 | MEN1 (0.64) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL2305794 | 0.76 | MEN1 (0.59) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL26127761 | 0.76 | MEN1 (0.59) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL11253767 | 0.76 | MEN1 (0.59) | MEN1KMT2ATDP1MAOACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662960-B2 | Beta-strand mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2010-02-16 | — | — | US | disclosed |
| EP-1751131-A1 | MTP INHIBITING ARYL PIPERIDINES OR PIPERAZINES SUBSTITUTED WITH 5-MEMBERED HETEROCYCLES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005085226-A1 | MTP INHIBITING ARYL PIPERIDINES OR PIPERAZINES SUBSTITUTED WITH 5-MEMBERED HETEROCYCLES | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-09-15 | — | — | WO | disclosed |