Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.43 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DUT | P33316 | 2/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.37 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545741 | 0.81 | SLC28A1 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3NT5E | |
| SCHEMBL9221120 | 0.80 | NT5E (0.36) | SLC28A1SLC28A2SLC29A1SLC28A3NT5E | |
| SCHEMBL6256517 | 0.80 | NT5E (0.36) | SLC28A1SLC28A2SLC29A1SLC28A3NT5E | |
| SCHEMBL10647012 | 0.78 | P2RY2 (0.51) | P2RY2P2RY4CYP3A4CYP2C9P2RY12 | |
| SCHEMBL9556690 | 0.76 | SLC28A1 (0.44) | SLC28A1SLC28A2SLC29A1SLC28A3NT5E | |
| SCHEMBL8887359 | 0.75 | POLB (0.45) | SLC28A1SLC28A2SLC29A1SLC28A3NT5E | |
| SCHEMBL6714493 | 0.75 | SLC28A1 (0.49) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL17372031 | 0.75 | SLC28A1 (0.49) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL17372034 | 0.75 | SLC28A1 (0.49) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL4074082 | 0.74 | SLC28A1 (0.40) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043208-A1 | Crystal structure of erythrocyte binding domain of EBA-175 | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2007-02-22 | — | — | US | claimed |
| US-5071974-A | COMPOSITIONS AND METHODS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES HAVING 5'-PHOSPHORYLATED TERMINI | AMOCO CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0266168-A2 | Compositions and methods for the synthesis of oligonucleotides having 5'-phosphorylated termini | AMOCO CORPORATION (US) | 1988-05-04 | — | — | EP | disclosed |