SCHEMBL6545741

SCHEMBL6545741

CC(=O)[C@@]1(O)[C@@H](CO)O[C@@H](n2ccc(=O)[nH]c2=O)[C@@]1(O)C(C)=O

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.46
SLC28A2 O43868 1/20 0.46
SLC29A1 Q99808 1/20 0.46
SLC28A3 Q9HAS3 1/20 0.46
P2RY2 P41231 6/20 0.41
P2RY4 P51582 2/20 0.41
POLA1 P09884 1/20 0.36
NT5E P21589 1/20 0.36
DUT P33316 1/20 0.35
P2RY14 Q15391 2/20 0.35
P2RY6 Q15077 4/20 0.35
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9556690 0.90 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL6220748 0.86 P2RY2 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL30534780 0.82 DUT (0.55) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL5547202 0.81 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL4074082 0.80 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL4083099 0.80 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL4083526 0.80 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL5531485 0.80 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL25233938 0.80 SLC28A1 (0.48) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL2985708 0.80 SLC28A1 (0.48) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4284341-B1 URIDINE TRIACETATE AMORPHOUS FORMULATION PHARMA CINQ LLC (US) 2026-04-08 EP disclosed
US-12577270-B2 2′,3′-diacetyluridine substituted with acetoacetyl at the 5′ position PHARMA CINQ, LLC (US) 2026-03-17 US disclosed
EP-4667478-A1 2',3'-DIACETYLURIDINE SUBSTITUTED WITH ACETOACETYL AT THE 5' POSITION Pharma Cinq, LLC (US) 2025-12-24 EP disclosed
EP-4210709-B1 2',3'-DIACETYLURIDINE SUBSTITUTED WITH ACETOACETYL AT THE 5' POSITION PHARMA CINQ LLC (US) 2025-10-29 EP disclosed
US-20240299434-A1 URIDINE TRIACETATE AMORPHOUS FORMULATION PHARMA CINQ, LLC 2024-09-12 US disclosed
EP-4210709-A4 2',3'-DIACETYLURIDINE SUBSTITUTED WITH ACETOACETYL AT THE 5' POSITION Pharma Cinq, LLC (US) 2024-09-04 EP disclosed
US-20230357304-A1 2′,3′-Diacetyluridine Substituted With Acetoacetyl at the 5′ Position WELLSTAT THERAPEUTICS CORPORATION 2023-11-09 US disclosed
EP-4210709-A1 2',3'-DIACETYLURIDINE SUBSTITUTED WITH ACETOACETYL AT THE 5' POSITION Wellstat Therapeutics Corporation (US) 2023-07-19 EP disclosed
CN-116157133-A 2',3' -diacetyluridine substituted with acetoacetyl group at 5' position 维尔斯达医疗公司 2023-05-23 CN disclosed
CN-116157133-A 2',3' -diacetyluridine substituted with acetoacetyl group at 5' position 维尔斯达医疗公司 2023-05-23 CN disclosed
US-20040057962-A1 Immunogenic complex BT PHARMA (FR) 2004-03-25 US disclosed
EP-1379280-A2 IMMUNOGENIC COMPLEX Timmerman, Benedikt (FR) 2004-01-14 EP disclosed
WO-2002053189-A2 IMMUNOGENIC COMPLEX TIMMERMAN BENEDIKT (FR) 2002-07-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577270-B2 2′,3′-diacetyluridine substituted with acetoacetyl at the 5′ position UQCRC2, ACAT1, ACAA2 SLC28A1 441/4885SLC28A2 268/4885SLC29A1 307/4885
US-20230357304-A1 2′,3′-Diacetyluridine Substituted With Acetoacetyl at the 5′ Position ACAT1, ACADVL, ACAA2 SLC28A1 1416/4885SLC28A2 1134/4885SLC29A1 1327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.