SCHEMBL5547255

SCHEMBL5547255

Cc1cc(C)c(-c2ccccc2)c(-c2ccccc2)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
ALDH1A1 P00352 3/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
PKM P14618 1/20 0.44
RAB9A P51151 1/20 0.44
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
AKT2 P31751 2/20 0.38
BRD4 O60885 2/20 0.38
CHEK1 O14757 1/20 0.38
BRD2 P25440 1/20 0.38
ESR2 Q92731 1/20 0.38
ACHE P22303 2/20 0.37
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9721459 0.90 MAPT (0.47) MAPTALDH1A1KMT2AKDM4EMEN1
SCHEMBL5951481 0.86 MAPT (0.44) MAPTALDH1A1KMT2AKDM4EMEN1
SCHEMBL5551256 0.85 MAPT (0.42) MAPTALDH1A1KMT2AKDM4EMEN1
SCHEMBL9695782 0.82 ESR2 (0.44) MAPTALDH1A1KMT2AKDM4EMEN1
SCHEMBL1470574 0.81 MAPT (0.44) MAPTALDH1A1KMT2AKDM4EMEN1
SCHEMBL7649546 0.80 PDE4B (0.43) MAPTALDH1A1KMT2AKDM4EMEN1
SCHEMBL3145455 0.79 MAPT (0.42) MAPTALDH1A1KMT2AKDM4EMEN1
SCHEMBL5551460 0.77 ESR2 (0.44) MAPTALDH1A1KMT2AKDM4EMEN1
SCHEMBL20873646 0.77 MAPT (0.43) MAPTALDH1A1KMT2AKDM4EMEN1
SCHEMBL13700778 0.77 L3MBTL1 (0.55) MAPTALDH1A1KMT2AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7295802-B2 Image forming apparatus using a cleaning unit for preventing noises RICOH COMPANY, LTD (JP) 2007-11-13 US disclosed
US-20070110488-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDE THEREFOR KABATA TOSHIYUKI 2007-05-17 US disclosed
US-7181156-B2 Image forming apparatus using a cleaning member for preventing noises and process cartridge therefor RICOH COMPANY, LTD. (JP) 2007-02-20 US disclosed
US-20050069357-A1 Image forming apparatus and process cartridge therefor RICOH COMPANY, LTD (JP) 2005-03-31 US disclosed
US-5561016-A HAVING PHOTOCONDUCTIVE LAYER CONTAINING CHARGE GENERATING MATERIAL, POLYVINYL BUTYRAL BINDER, CHARGE TRANSPORTING MATERIAL AND BIPHENYL(OR DERIVATIVE) ON ELECTROCONDUCTIVE SUPPORT RICOH COMPANY, LTD. (JP) 1996-10-01 US disclosed