Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1470574 | 0.93 | MAPT (0.44) | MAPTLMNAHTTALDH1A1CHEK1 | |
| SCHEMBL5551256 | 0.93 | MAPT (0.42) | MAPTLMNAHTTALDH1A1CHEK1 | |
| SCHEMBL5951481 | 0.84 | MAPT (0.44) | MAPTLMNAHTTALDH1A1CHEK1 | |
| SCHEMBL3974332 | 0.83 | AKT2 (0.48) | MAPTHTTALDH1A1CHEK1AKT2 | |
| SCHEMBL3362430 | 0.81 | ALDH1A1 (0.41) | MAPTALDH1A1ATMHPGDMEN1 | |
| SCHEMBL24570925 | 0.79 | BRD4 (0.44) | MAPTLMNAHTTALDH1A1CHEK1 | |
| SCHEMBL5547255 | 0.79 | MAPT (0.44) | MAPTLMNAHTTALDH1A1CHEK1 | |
| SCHEMBL29473774 | 0.78 | ESR2 (0.38) | MAPTLMNAHTTALDH1A1CHEK1 | |
| SCHEMBL28586108 | 0.78 | ESR2 (0.38) | MAPTLMNAHTTALDH1A1CHEK1 | |
| SCHEMBL12999310 | 0.78 | MEN1 (0.38) | MAPTLMNAHTTALDH1A1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7641975-B2 | Hardeners | BAYER MATERIALSCIENCE AG (DE) | 2010-01-05 | — | — | US | disclosed |
| US-20050123768-A1 | Hardeners | BAYER MATERIALSCIENCE AG | 2005-06-09 | — | — | US | disclosed |