Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5547419 | 0.93 | EGFR (0.41) | GLAEGFRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL19695792 | 0.85 | ALDH1A1 (0.42) | GLAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL25421283 | 0.83 | EGFR (0.53) | GLAEGFRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL3422030 | 0.83 | EGFR (0.53) | GLAEGFRALDH1A1SMN1; SMN2KMT2A | |
| Bromide SCHEMBL14247934 | 0.82 | EGFR (0.52) | GLAEGFRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6601404 | 0.82 | EGFR (0.54) | GLAEGFRALDH1A1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL21814218 | 0.81 | EGFR (0.56) | GLAEGFRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL5059161 | 0.81 | EGFR (0.53) | GLAEGFRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL19695790 | 0.81 | SMN1; SMN2 (0.42) | GLAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5054607 | 0.80 | EGFR (0.48) | GLAEGFRALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806350-A2 | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents | BRACCO International B.V. (NL) | 2007-07-11 | — | — | EP | disclosed |
| EP-1153029-B1 | AMPHIPATIC POLYCARBOXYLIC CHELATES AND COMPLEXES WITH PARAMAGNETIC METALS AS MRI CONTRAST AGENTS | BRACCO INT BV (NL) | 2007-01-10 | — | — | EP | disclosed |