Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5968494 | 1.00 | TSHR (0.35) | TSHRMEN1KMT2ALMNATHRB | |
| SCHEMBL3651917 | 0.89 | LMNA (0.32) | LMNATHRBCYP2C19 | |
| SCHEMBL3648749 | 0.89 | LMNA (0.32) | LMNATHRBCYP2C19 | |
| SCHEMBL794100 | 0.81 | MEN1 (0.34) | TSHRMEN1KMT2A | |
| SCHEMBL793843 | 0.81 | MEN1 (0.34) | TSHRMEN1KMT2A | |
| SCHEMBL1571074 | 0.79 | MEN1 (0.32) | TSHRMEN1KMT2ALMNATHRB | |
| SCHEMBL1693080 | 0.78 | MEN1 (0.33) | TSHRMEN1KMT2A | |
| SCHEMBL1692713 | 0.78 | MEN1 (0.33) | TSHRMEN1KMT2A | |
| SCHEMBL6414470 | 0.78 | MEN1 (0.33) | TSHRMEN1KMT2ALMNACYP2C19 | |
| SCHEMBL6414862 | 0.78 | MEN1 (0.33) | TSHRMEN1KMT2ALMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597264-A2 | ANTIPARASITIC TERPENE ALKALOIDS | Pfizer Limited (GB) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004072086-A2 | ANTIPARASITIC TERPENE ALKALOIDS | PFIZER LIMITED (GB) | 2004-08-26 | — | — | WO | disclosed |