Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6226618 | 0.83 | L3MBTL1 (0.41) | KMT2APDE2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL160634 | 0.81 | MAPT (0.36) | HTTKDM4EKMT2APDE2AALDH1A1 | |
| SCHEMBL160761 | 0.80 | L3MBTL1 (0.37) | SMN1; SMN2KDM4EPDE2AALDH1A1HPGD | |
| SCHEMBL8810300 | 0.80 | L3MBTL1 (0.36) | KDM4EPDE2AALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL28130967 | 0.77 | PTPN1 (0.31) | — | |
| SCHEMBL5553179 | 0.76 | KDM4E (0.40) | KDM4EPIM1ALDH1A1MAPT | |
| SCHEMBL28088212 | 0.76 | ACHE (0.40) | SMN1; SMN2KDM4EPDE2AALDH1A1HPGD | |
| SCHEMBL16395343 | 0.75 | PPARG (0.32) | ALDH1A1 | |
| SCHEMBL7997628 | 0.75 | PTPN1 (0.35) | KMT2AALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL5551862 | 0.74 | HTR2C (0.44) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302417-A | NLRP3 inhibitors | PTC医疗公司 | 2024-07-05 | — | — | CN | disclosed |
| EP-1780211-A2 | Vanilloid receptor ligands and their use in treatments | Amgen Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| EP-1775295-A1 | Vanilloid receptor ligands and their use in treatments | Amgen Inc. (US) | 2007-04-18 | — | — | EP | disclosed |