Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.60 |
| ▸ | MEN1 | O00255 | 11/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 10/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59885 | 0.87 | KMT2A (0.71) | KMT2AMEN1RAB9ANPC1HSP90AA1 | |
| SCHEMBL29655504 | 0.87 | KMT2A (0.71) | KMT2AMEN1RAB9ANPC1HSP90AA1 | |
| SCHEMBL5042615 | 0.87 | KMT2A (0.71) | KMT2AMEN1RAB9ANPC1HSP90AA1 | |
| SCHEMBL8509244 | 0.87 | KMT2A (0.71) | KMT2AMEN1RAB9ANPC1HSP90AA1 | |
| SCHEMBL29836998 | 0.87 | KMT2A (0.71) | KMT2AMEN1RAB9ANPC1HSP90AA1 | |
| SCHEMBL2845788 | 0.87 | KMT2A (0.71) | KMT2AMEN1RAB9ANPC1HSP90AA1 | |
| SCHEMBL11693578 | 0.87 | KMT2A (0.71) | KMT2AMEN1RAB9ANPC1HSP90AA1 | |
| Methacrylic Acid SCHEMBL554250 | 0.85 | MAPT (0.58) | KMT2AMEN1RAB9ANPC1HSP90AA1 | |
| Azobenzene SCHEMBL509328 | 0.80 | ALDH1A1 (0.57) | KMT2AMEN1RAB9ANPC1HSP90AA1 | |
| Azobenzene SCHEMBL30414107 | 0.80 | ALDH1A1 (0.57) | KMT2AMEN1RAB9ANPC1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041165-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-02-16 | — | — | US | disclosed |
| US-20120035337-A1 | NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS | KEY MEDICAL TECHNOLOGIES, INC. (US) | 2012-02-09 | — | — | US | disclosed |
| US-8048972-B2 | Nanohybrid polymers for ophthalmic applications | KEY MEDICAL TECHNOLOGIES, INC. (US) | 2011-11-01 | — | — | US | disclosed |