Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 20/20 | 0.62 |
| ▸ | FNTB | P49356 | 20/20 | 0.62 |
| ▸ | PGGT1B | P53609 | 17/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665146 | 0.81 | FNTA (0.73) | FNTAFNTBPGGT1B | |
| SCHEMBL7159262 | 0.80 | FNTA (0.67) | FNTAFNTBPGGT1B | |
| SCHEMBL7593586 | 0.79 | FNTA (0.55) | FNTAFNTBPGGT1B | |
| SCHEMBL7592877 | 0.78 | FNTA (0.51) | FNTAFNTBPGGT1B | |
| SCHEMBL8005220 | 0.78 | FNTA (0.62) | FNTAFNTBPGGT1B | |
| SCHEMBL5583298 | 0.77 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL3505604 | 0.77 | FNTA (0.65) | FNTAFNTBPGGT1B | |
| SCHEMBL7593579 | 0.76 | FNTA (0.50) | FNTAFNTBPGGT1B | |
| SCHEMBL7592794 | 0.75 | FNTA (0.67) | FNTAFNTBPGGT1B | |
| SCHEMBL8090861 | 0.74 | FNTA (0.53) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1744751-A2 | METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2007-01-24 | — | — | EP | claimed |
| WO-2005089502-A2 | METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2005-09-29 | — | — | WO | claimed |
| JP-2002540072-A | — | — | 2002-11-26 | — | — | JP | claimed |
| EP-1165082-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-06-12 | — | — | EP | claimed |
| US-6358956-B1 | IMIDAZOLYLALKYL-1-PIPERAZINE DERIVATIVES; FARNESYL-PROTEIN AND GERANYLGERANYL TRANSFERASE INHIBITORS; ANTICARCINOGENIC AGENTS | MERCK & CO., INC. | 2002-03-19 | — | — | US | claimed |
| EP-1165082-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2000051611-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-09-08 | — | — | WO | claimed |
| US-6358956-B1 | IMIDAZOLYLALKYL-1-PIPERAZINE DERIVATIVES; FARNESYL-PROTEIN AND GERANYLGERANYL TRANSFERASE INHIBITORS; ANTICARCINOGENIC AGENTS | MERCK & CO., INC. | 2002-03-19 | — | — | US | disclosed |