Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.62 |
| ▸ | FNTB | P49356 | 18/20 | 0.62 |
| ▸ | PGGT1B | P53609 | 13/20 | 0.62 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.54 |
| ▸ | NRAS | P01111 | 1/20 | 0.53 |
| ▸ | HRAS | P01112 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548991 | 0.79 | CYP11B1 (0.64) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7665146 | 0.79 | FNTA (0.73) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7747228 | 0.78 | CYP11B1 (0.62) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL5548038 | 0.78 | FNTA (0.62) | FNTAFNTBPGGT1B | |
| SCHEMBL5583298 | 0.76 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL7743768 | 0.76 | FNTA (0.66) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7839795 | 0.76 | FNTA (0.59) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7738189 | 0.75 | FNTA (0.64) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL3505604 | 0.74 | FNTA (0.65) | FNTAFNTBPGGT1B | |
| SCHEMBL7662196 | 0.74 | FNTA (0.68) | FNTAFNTBPGGT1BCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019530-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-07-19 | — | — | EP | claimed |
| WO-1999010524-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1999-03-04 | — | — | WO | claimed |
| US-6103487-A | DETECTING MODULATORS THAT SUPPRESS THE ACTIVITY OF A TRANSFERASES; ANTICARCINOGENIC AGENTS | MERCK & CO., INC. (US) | 2000-08-15 | — | — | US | disclosed |
| EP-1019530-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-2000016626-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 2000-03-30 | — | — | WO | disclosed |
| WO-1999010524-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1999-03-04 | — | — | WO | disclosed |