Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2194043 | 0.82 | SYK (0.46) | FLT1EPHA2KDREPHB4EGFR | |
| Hydrochloric Acid SCHEMBL2195908 | 0.81 | SYK (0.45) | FLT1EPHA2KDREPHB4EGFR | |
| SCHEMBL27298989 | 0.79 | FLT1 (0.41) | FLT1EPHA2KDREPHB4EGFR | |
| SCHEMBL6237515 | 0.77 | MAPT (0.48) | NPC1RAB9AMAPTKMT2AS1PR4 | |
| SCHEMBL23516857 | 0.73 | MRGPRX4 (0.47) | FLT1EPHA2KDREPHB4NMT1 | |
| SCHEMBL27192266 | 0.73 | EGFR (0.40) | FLT1EPHA2KDREPHB4EGFR | |
| SCHEMBL9873609 | 0.71 | FLT1 (0.38) | FLT1EPHA2KDREPHB4EGFR | |
| SCHEMBL31379484 | 0.71 | GRM5 (0.45) | FLT1EPHA2KDREPHB4NMT1 | |
| SCHEMBL6920659 | 0.70 | NPC1 (0.60) | MRGPRX4NPC1RAB9AMAPTKMT2A | |
| SCHEMBL31379494 | 0.70 | FLT1 (0.38) | FLT1EPHA2KDREPHB4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799653-A2 | NOVEL HETEROCYCLES | Bayer Pharmaceuticals Corporation (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006023843-A2 | NOVEL HETEROCYCLES | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-03-02 | — | — | WO | disclosed |