Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2194043 | 0.77 | SYK (0.46) | FLT1EPHA2KDREPHB4NOS3 | |
| SCHEMBL31379494 | 0.76 | FLT1 (0.38) | FLT1EPHA2KDREPHB4NOS3 | |
| Hydrochloric Acid SCHEMBL2195908 | 0.76 | SYK (0.45) | FLT1EPHA2KDREPHB4NOS3 | |
| SCHEMBL9873250 | 0.75 | SYK (0.64) | SYKEGFRALDH1A1HTT | |
| SCHEMBL27096786 | 0.75 | NOS3 (0.39) | FLT1EPHA2KDREPHB4NOS3 | |
| SCHEMBL30729942 | 0.75 | NOS3 (0.39) | FLT1EPHA2KDREPHB4NOS3 | |
| SCHEMBL23516857 | 0.74 | MRGPRX4 (0.47) | FLT1EPHA2KDREPHB4NOS3 | |
| SCHEMBL9872127 | 0.74 | SYK (0.37) | SYKMRGPRX4HRH4HPGDHTT | |
| SCHEMBL31379547 | 0.72 | FLT1 (0.35) | FLT1EPHA2KDREPHB4NOS3 | |
| SCHEMBL5548307 | 0.71 | FLT1 (0.41) | FLT1EPHA2KDREPHB4NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017213-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0351641-A1 | 1-Phenylpyrrole | NIHON BAYER AGROCHEM K.K. (JP) | 1990-01-24 | — | — | EP | disclosed |