SCHEMBL5548696

SCHEMBL5548696

CC[Si](Cl)(CC)C1C(C(C)C)=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc21

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14382402 0.89
SCHEMBL5549218 0.88 BRD4 (0.30)
SCHEMBL5608064 0.87
SCHEMBL30541994 0.87 NPC1 (0.33)
SCHEMBL1799580 0.87 NPC1 (0.33)
SCHEMBL5607400 0.86
SCHEMBL3402757 0.85 NR1H4 (0.31) NR1H4
SCHEMBL5552751 0.84 NPC1 (0.34) NR1H4
SCHEMBL27337741 0.84 NPC1 (0.34) NR1H4
SCHEMBL3401848 0.84 NR1H4 (0.31) NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4029872-B1 TRANSITION METAL COMPOUND, METHOD FOR PREPARING THE SAME, AND CATALYST COMPOSITION COMPRISING THE SAME LG CHEMICAL LTD (KR) 2023-11-22 EP disclosed
EP-2915824-B1 METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2022-05-25 EP disclosed
EP-2915824-A1 METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS Lummus Novolen Technology Gmbh (DE) 2015-09-09 EP disclosed
US-7285608-B2 Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-10-23 US disclosed
EP-1740622-A2 METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS Novolen Technology Holdings C.V. (NL) 2007-01-10 EP disclosed
WO-2005105863-A2 METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2005-11-10 WO disclosed
US-20050239979-A1 Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2005-10-27 US disclosed