Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3434629 | 0.91 | NR1H4 (0.30) | NR1H4 | |
| SCHEMBL3400017 | 0.89 | PTAFR (0.33) | NR1H4BRD4CREBBP | |
| SCHEMBL3402757 | 0.87 | NR1H4 (0.31) | NR1H4BRD4CREBBP | |
| SCHEMBL7196862 | 0.86 | SMN1; SMN2 (0.34) | NR1H4BRD4CREBBP | |
| SCHEMBL5548696 | 0.84 | NR1H4 (0.30) | NR1H4 | |
| SCHEMBL3425601 | 0.83 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL3398271 | 0.81 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL3397237 | 0.79 | — | — | |
| SCHEMBL3400108 | 0.79 | TSHR (0.32) | — | |
| SCHEMBL7783132 | 0.79 | BRD4 (0.35) | BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235071-A2 | METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO AND COPOLYMERS | Novolen Technology Holdings, C.V. (NL) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009054833-A2 | METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO AND COPOLYMERS | NOVOLEN TECHNOLOGY HOLDINGS, C.V. (NL) | 2009-04-30 | — | — | WO | disclosed |