SCHEMBL5548745

SCHEMBL5548745

CC[Sn](CC)(Oc1ccccc1)O[Sn](CC)(CC)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.39
CA4 P22748 1/20 0.39
TSHR P16473 1/20 0.36
KCNA3 P22001 1/20 0.36
CHRNB2 P17787 2/20 0.35
CHRNB4 P30926 2/20 0.35
CHRNA3 P32297 2/20 0.35
CHRNA7 P36544 2/20 0.35
CHRNA4 P43681 2/20 0.35
KCNH2 Q12809 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
TP53 P04637 1/20 0.33
LMNA P02545 1/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465078 0.79 LTA4H (0.44) LTA4HKCNA3KCNH2LMNA
SCHEMBL2696251 0.77 LTA4H (0.43) LTA4HTSHRKCNH2LMNA
SCHEMBL11407618 0.76 CA4 (0.42) LTA4HCA4TSHRKCNA3CHRNB2
SCHEMBL701779 0.74 LTA4H (0.47) LTA4HCA4KCNA3KCNH2LMNA
SCHEMBL8619647 0.69 LTA4H (0.39) LTA4HKCNA3KCNH2LMNA
SCHEMBL8042127 0.69 LTA4H (0.39) LTA4HKCNA3KCNH2LMNA
SCHEMBL2698710 0.69 CA4 (0.43) LTA4HCA4TSHRKCNA3KCNH2
SCHEMBL701409 0.67 LTA4H (0.34) LTA4HCA4TSHRKCNA3CHRNB2
SCHEMBL151768 0.66 LTA4H (0.50) LTA4HCA4TSHRKCNA3L3MBTL1
SCHEMBL705052 0.65 LTA4H (0.47) LTA4HCA4KCNA3KCNH2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0890596-B1 Process for the preparation of poly (arylcarbonate)s GEN ELECTRIC (US) 2007-12-05 EP claimed