SCHEMBL8619647

SCHEMBL8619647

CCCC[Sn](Cl)(CCCC)O[Sn](CCCC)(CCCC)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.39
MLNR O43193 1/20 0.33
NR1I2 O75469 1/20 0.33
ESR1 P03372 1/20 0.33
NR3C1 P04150 1/20 0.33
PGR P06401 1/20 0.33
ADRB2 P07550 1/20 0.33
CHRM2 P08172 1/20 0.33
ADRB1 P08588 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
CHRM3 P20309 1/20 0.33
MAOA P21397 1/20 0.33
CNR1 P21554 1/20 0.33
SLC6A2 P23975 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465078 0.88 LTA4H (0.44) LTA4HMLNRNR1I2ESR1NR3C1
SCHEMBL701779 0.84 LTA4H (0.47) LTA4HMLNRNR1I2ESR1NR3C1
SCHEMBL2696251 0.81 LTA4H (0.43) LTA4HMLNRNR1I2ESR1NR3C1
SCHEMBL8042127 0.81 LTA4H (0.39) LTA4HMLNRNR1I2ESR1NR3C1
SCHEMBL29134992 0.75 LTA4H (0.40) LTA4HMLNRNR1I2ESR1NR3C1
SCHEMBL8621498 0.75 LTA4H (0.34) LTA4H
SCHEMBL5548753 0.75 KCNH2 (0.36) DRD2HTR2ADRD3KCNH2ALDH1A1
SCHEMBL705052 0.73 LTA4H (0.47) LTA4HMLNRNR1I2ESR1NR3C1
SCHEMBL3098844 0.73 ELANE (0.50) HTTALDH1A1MAPTGAAKMT2A
SCHEMBL4909630 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0601885-B1 Biodegradable optically active polymer of lactones and process for production thereof TAKASAGO PERFUMERY CO LTD (JP) 1998-06-03 EP disclosed
EP-0612780-B1 Process for producing poly(3-hydroxybutyric acid) TAKASAGO PERFUMERY CO LTD (JP) 1998-05-20 EP disclosed
US-5516883-A POLYLACTONES TAKASAGO INTERNATIONAL CORPORATION (JP) 1996-05-14 US disclosed
US-5461139-A Ring-opening polymerization of of beta-butyrolactone and cyclic carbonate using distannoxane catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 1995-10-24 US disclosed
US-5430125-A Ring opening polymerization of beta butyrolalactone in the presence of a distannoxane derivative, a tin carboxylate and a di-lower alkyltin oxide TAKASAGO INTERNATIONAL CORPORATION (JP) 1995-07-04 US disclosed
EP-0640637-A1 Biodegradable optically-active polyester carbonates Takasago International Corporation (JP) 1995-03-01 EP disclosed
EP-0612780-A2 Process for producing poly(3-hydroxybutyric acid) Takasago International Corporation (JP) 1994-08-31 EP disclosed
EP-0601885-A2 Biodegradable optically active polymer of lactones and process for production thereof Takasago International Corporation (JP) 1994-06-15 EP disclosed