Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5943678 | 0.83 | ALDH1A1 (0.75) | ALDH1A1ALOX15TDP1SMN1; SMN2HPGD | |
| SCHEMBL28329681 | 0.81 | ALDH1A1 (0.54) | ALDH1A1ALOX15KIF11 | |
| SCHEMBL9342695 | 0.81 | ALDH1A1 (0.54) | ALDH1A1ALOX15MEN1KMT2AESR1 | |
| SCHEMBL9342853 | 0.81 | ALDH1A1 (0.54) | ALDH1A1ALOX15MEN1KMT2AESR1 | |
| SCHEMBL9342729 | 0.81 | ALDH1A1 (0.54) | ALDH1A1ALOX15MEN1KMT2AESR1 | |
| SCHEMBL17320466 | 0.80 | RORC (0.43) | ALDH1A1LPLLIPGPLK1TDP1 | |
| SCHEMBL8578305 | 0.79 | ALDH1A1 (0.62) | ALDH1A1ALOX15TDP1HPGDMEN1 | |
| SCHEMBL9246676 | 0.79 | ESR1 (0.39) | ALDH1A1LPLLIPGPLK1TDP1 | |
| SCHEMBL23109754 | 0.78 | ALDH1A1 (0.50) | ALDH1A1ALOX15ESR1TP53 | |
| SCHEMBL9875215 | 0.78 | ALDH1A1 (0.50) | ALDH1A1ALOX15MEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494984-B1 | PROCESS FOR PREPARING PHENOLS | INEOS PHENOL GMBH & CO KG (DE) | 2007-09-12 | — | — | EP | disclosed |
| US-6875898-B2 | Process for preparing phenols | INEOS PHENOL GMBH & CO. KG (DE) | 2005-04-05 | — | — | US | disclosed |
| EP-1494984-A1 | PROCESS FOR PREPARING PHENOLS | INEOS Phenol GmbH & Co. KG (DE) | 2005-01-12 | — | — | EP | disclosed |
| US-20030220528-A1 | Process for preparing phenols | BARCLAYS BANK PLC (IN ITS CAPACITY AS SECURITY TRUSTEE FOR ITSELF AND OTHER SECURED PARTIES) (GB) | 2003-11-27 | — | — | US | disclosed |
| WO-2003084909-A1 | PROCESS FOR PREPARING PHENOLS | INEOS PHENOL GMBH & CO. KG (DE) | 2003-10-16 | — | — | WO | disclosed |
| EP-1350782-A1 | Process for the recovery of phenol from alkylaryl hydroperoxide decomposition products | INEOS Phenol GmbH & Co. KG (DE) | 2003-10-08 | — | — | EP | disclosed |
| EP-1199295-B1 | Process for the cleavage of alkylaryl hydroperoxides | INEOS PHENOL GMBH & CO KG (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6444861-B1 | Process for the cleavage of alkylaryl hydroperoxides | PHENOLCHEMIE GMBH & CO. KG (DE) | 2002-09-03 | — | — | US | disclosed |
| EP-1199295-A1 | Process for the cleavage of alkylaryl hydroperoxides | INEOS Phenol GmbH & Co. KG (DE) | 2002-04-24 | — | — | EP | disclosed |
| US-20020045781-A1 | Process for the cleavage of alkylaryl hydroperoxides | PHENOLCHEMIE GMBH & CO. KG (DE) | 2002-04-18 | — | — | US | disclosed |
| EP-0032255-B1 | PROCESS FOR THE DIRECT NEUTRALISATION OF A REACTION MIXTURE RESULTING FROM THE ACID CLEAVAGE OF AN ALPHA-HYDROXY DERIVATIVE OF AN ALKYL-SUBSTITUTED AROMATIC HYDROCARBON AND THE REMOVAL OF THE FORMED SALT | UOP INC. (US) | 1984-03-14 | — | — | EP | disclosed |
| US-4333801-A | Recovery of a cumene/alpha-methylstyrene fraction from a mixture thereof with phenol and water | UOP INC. (US) | 1982-06-08 | — | — | US | disclosed |
| EP-0032255-A1 | Process for the direct neutralisation of a reaction mixture resulting from the acid cleavage of an alpha-hydroxy derivative of an alkyl-substituted aromatic hydrocarbon and the removal of the formed salt | UOP INC. (US) | 1981-07-22 | — | — | EP | disclosed |
| US-4262151-A | Process for the recovery of phenol from a reaction mixture resulting from the acid cleavage of cumene hydroperoxide | UOP INC. (US) | 1981-04-14 | — | — | US | disclosed |