Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 2/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5550486 | 0.77 | TLR8 (0.41) | — | |
| SCHEMBL1021866 | 0.76 | CHRNB4 (0.38) | CHRNB4CHRNA3CHRNA7PRKCIACMSD | |
| SCHEMBL5549746 | 0.75 | RARB (0.40) | DRD3PTGS2 | |
| SCHEMBL1019334 | 0.74 | CHRNB4 (0.36) | CHRNB4CHRNA3CHRNA7PRKCILPL | |
| SCHEMBL1019331 | 0.74 | CHRNB4 (0.36) | CHRNB4CHRNA3CHRNA7PRKCILPL | |
| SCHEMBL14489482 | 0.73 | CHRNB4 (0.53) | CHRNB4CHRNA3CHRNA7PRKCIENPP2 | |
| SCHEMBL6845384 | 0.71 | LPL (0.53) | LPLLIPGENPP2 | |
| SCHEMBL27687396 | 0.70 | CHRNB4 (0.34) | CHRNB4CHRNA3CHRNA7PRKCIDRD2 | |
| SCHEMBL5550509 | 0.70 | MAPK14 (0.46) | PTGS2 | |
| SCHEMBL199210 | 0.68 | LPL (0.52) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841729-A1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | Amorepacific Corporation (KR) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006059867-A1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | AMOREPACIFIC CORPORATION (KR) | 2006-06-08 | — | — | WO | disclosed |