Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL8171145 | 0.92 | S100B (0.46) | S100BALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL5502903 | 0.90 | S100B (0.50) | S100BALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL10955324 | 0.89 | S100B (0.60) | S100BALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL29740664 | 0.89 | S100B (0.60) | S100BALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL5500237 | 0.88 | S100B (0.49) | S100BALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL6389523 | 0.84 | S100B (0.45) | S100BALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL16003239 | 0.84 | S100B (0.55) | S100BALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL30491146 | 0.84 | S100B (0.65) | S100BALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL33756 | 0.84 | S100B (0.65) | S100BALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL16104767 | 0.82 | EGFR (0.39) | S100BALDH1A1TDP1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9005923-A | — | — | None | — | — | JP | disclosed |
| US-RE48140-E1 | Furanone derivative | CARNA BIOSCIENCES, INC. (JP) | 2020-08-04 | — | — | US | disclosed |
| EP-2692728-B1 | NOVEL FURANONE DERIVATIVE | CARNA BIOSCIENCES INC (JP) | 2018-07-04 | — | — | EP | disclosed |
| US-RE46815-E1 | Furanone derivative | CARNA BIOSCIENCES, INC. (JP) | 2018-05-01 | — | — | US | disclosed |
| US-8742113-B2 | Furanone derivative | SBI BIOTECH CO., LTD. (JP) | 2014-06-03 | — | — | US | disclosed |
| EP-2692728-A1 | NOVEL FURANONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2014-02-05 | — | — | EP | disclosed |
| US-20140018533-A1 | NOVEL FURANONE DERIVATIVE | CARNA BIOSCIENCES, INC. (JP) | 2014-01-16 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
| JP-H095923-A | SILVER HALIDE COLOR PHOTOGRAPHIC SENSITIVE MATERIAL AND IMAGE FORMING METHOD | FUJI PHOTO FILM CO LTD | 1997-01-10 | — | — | JP | disclosed |
| US-5158892-A | Antifogging agent | FUJI PHOTO FILM CO., LTD. (JP) | 1992-10-27 | — | — | US | disclosed |
| US-5021067-A | Rapid oxidation dyes for darkening hair; 5,6-dioxyindole derivatives | L'OREAL (FR) | 1991-06-04 | — | — | US | disclosed |
| US-4295853-A | EXTRACTING LIPOPEROXIDE FROM BLOOD OR SERUM, OXIDIZABLE COLOR REAGENT, COMPOUND OF MULTIVALENT METAL | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1981-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018533-A1 | NOVEL FURANONE DERIVATIVE | CYP11B1, OXER1, CYP11B2 | S100B 4622/4885ALDH1A1 345/4885TDP1 2903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.